Introduction: Biomedical waste is any solid, fluid or liquid waste, including container and any intermediate products, generated during diagnosis and treatment in the hospitals. At the same time health services may generate large quantity of wastes and byproducts that need to be handled safely and disposed of properly.

Materials and Method: The descriptive study was conducted with convenience sample of 50 staff nurses working at hospital in Agra. The semi structured questionnaire was prepared for interviewing the participant. It contains about the demographic profile such as age in years, religion, family income per month, type of family, marital status, previous exposure to education regarding Bio Medical Waste Management and the source of information on Bio Medical Waste Management.

Results: Among 50 samples the majority 26 (52%) were under the qualification of B.SC (N). with regard to total years of experience the majority 35 (70%) were fall in 0-5 years of experience. With regard to source of information about bio medical waste management the majority 40 (80%) got information through nursing education. With regard to availability of needle burner the majority 34 (68%) were having needle burner. With regard to Ward the majority 12 (24%) were from A & B and C & D ward. The study findings revealed that among 50 nurses 35 (70%) had adequate knowledge, 15 (30%) had moderate adequate knowledge and none of them had inadequate knowledge.

Conclusions: the need of comprehensive training programs regarding handling, segregation, transportation & storage of waste in colour bins until final disposal and treatment for all hospital staff is highly recommended to deal with this burning issue of bio-medical waste management.