author(s)
Athira T Devaraj and Rohini T

abstract
Hypokalemic Periodic Paralysis (HypoPP) is a condition that causes episodes of extreme muscle weakness typically beginning in childhood or adolescence. The disorder is three to four times more commonly clinically expressed in men. Mutations in the CACNA1S (calcium voltage-gated channel subunit alpha 1 S) or SCN4A (sodium voltage-gated channel alpha subunit 4) gene can cause Hypokalemic Periodic Paralysis. The primary form is genetic and follows an autosomal dominant pattern of inheritance. The secondary forms may complicate a number of medical disorders. Echocardiography, electromyography, muscle biopsy, lab investigations are useful for diagnosis. The treatment of choice is avoidance of triggering factors, adherence to a diet low in sodium, carbohydrate and rich in potassium, and with the use of oral potassium supplementation. Nurses have a great role to play in the management of a patient with HypoPP. For a comprehensive understanding of the condition ‘Hypokalemic Periodic Paralysis’ here is an article with the details of the disease - definition, other names, epidemiology, etiology, pathophysiology, clinical manifestations, diagnostic measures, management, complications and prevention presented along with a case report focusing on nursing management.