Sport is thought of an activity that is governed by a set of rules and that which is engaged in competitively, while doping is the idea of using banned natural or synthetic substance for the purpose of enhancing sports performance. Sports goes beyond a measure of athletic excellence and the winning of trophies, medals and cash awards has become a pride to the nation and sports persons. Sports teach us about honest endeavor, commitment and fair play. The use of performance enhancement drugs is very harmful to the body. Doping is a public health issue and not simply a problem inside the professional sports community. It is a complex and ancient phenomenon considering the vast variety of substances, supplied through both legal and illegal trading routes. It occurs in elite athletes but also affects amateur athletes and is generally considered as dangerous and unhealthy. The main objectives of the fight against doping in sports are the protection of health and fair competition in the defense of clean athletes.