The present study aimed to measure the current status of oncology hospital nurses' knowledge about genetics, genetics counseling, and the educational needs of nurses related to human genetics at Minia Governorate.

Setting: data were collected from oncology hospital at Minia Governorate.

Research design: Descriptive design has been utilized to carry out this study.

Sample: 75 staff nurses worked in oncology hospital and primary health center was included in the study. Data has been gathered by using Nurses professed knowledge of genetics and genetic counseling questionnaire.

Results: there are statistical massive distinction regarding genetic counseling experience among the studied nurses working in four area (surgery department, outpatient clinics, outpatient chemotherapy, and inpatient chemotherapy) in all items except information about current and future, revision of family history about approaches, local specialist, referral system, ability to review family genetic history, counseling to carrier of single disorder, ability to make recommendation, ability to provide recommendation, understanding basic ethics, and technique of genetic counseling.

Conclusion: the majority of samples in all area had information about genetic counseling for breast cancer. As regard surgery department all of the studied nurses had not any information and need genetic counseling about liver cancer, leukemia, uterine cancer, brain cancer, cell, lymphoma, diabetes mellitus, and hypertention. While had little information about colon cancer, bladder cancer, ovarian cancer, thyroid, and Acute lymphoblastic leukemia (ALL).

Recommendations: All nurses working in oncology hospital and primary health center are a need for continued education and training programs about genetic counseling.