The aim of the study to assess the effectiveness of structured teaching program on knowledge regarding kangaroo mother care on low-birth weight infants among post-natal mothers in a selected hospital at Dehradun. Convenient sampling technique was used to collect data from 50 postnatal mothers who were admitted in SMI Hospital. One group test pre-test and post-test design was used to evaluate the effectiveness of structure. Pre-test shows that most 32% mothers had inadequate knowledge, 64% had moderate level of knowledge and 4% had adequate knowledge. Post-test shows that all the postnatal mothers 50 (100%) attained moderate knowledge after the structured teaching program teaching program. Therefore, the study concluded that there was significant improvement in the knowledge of postnatal mothers which was due to the structured teaching program on KMC among postnatal mothers.