Background: Suicide is a significant public health issue. Yearly around 800,000 individuals end their own lives, and many more individuals attempt suicide. Nurses play an essential role in the health care sectors to encounter patients at risk of suicide behavior because nurses act on the frontlines and have the highest opportunities to recognize and interfere with suicide risk behavior.

Purpose: This study's main objectives are to identify psychiatric nursing knowledge, attitudes, and practices toward suicide risk behavior and determine the proactive measures related to suicide prevention.

Method: The present study is a quantitative method, a cross-section design.

The tool used to collect the data was a questionnaire. A convenience sample of 242 nurses who work in inpatient psychiatric and emergency departments in the Eradah and Mental Health complex were invited to participate in this study.

Results: The current study found that almost all nursing (79.3%) believe that they need to improve their knowledge, attitudes, and practices about suicide prevention and care, concerning nursing knowledge on how to manage and deal with the cases of suicide risk behavior, the results generally reveal that nursing has no sufficient knowledge, while they have positive attitudes and practices toward suicidal risk behavior.

Conclusion: The study encourages stakeholders to initiate nursing educational programs that involve practical and theoretical parts to all nursing degrees, aiming to raise their knowledge, attitudes, and practices about suicide prevention as well as to develop caring skills and establish nursing risk assessment tool to determine the level of suicidal risk behavior.