Introduction: Myocardial infarction is recognized as one of the leading causes of death worldwide. Depending on the extent of the heart muscle damages, the patient may experience significant disability or die as a result of myocardial infarction. Identifying early signs of myocardial infarction may aid in the early diagnosis of myocardial infarction.

Purpose: To assess the knowledge regarding early signs of myocardial infarction. To associate findings with selected demographic variables.

Methods: This was a Non experimental, exploratory research design and quantitative research approach. 100 adults were selected from urban areas of Pune City by non-probability purposive sampling technique. A self - structured questionnaire was used to assess knowledge with the observational checklist.

Results: Mean score of knowledge regarding early signs of myocardial infarction was 8.28 with 5.061401 standard deviation that show average knowledge and the ‘p’ value was more than the level of significance 0.05 so There is an association between age, income, occupation, dietary pattern, habits, exercise with knowledge. There is no any association between genders, weight, previous history of myocardial infarction, Family history of myocardial infarction with knowledge.

Conclusion: knowledge regarding early signs of myocardial infarction was average.